GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs10935120 | 1 | rs11919350 | chr3:134235970 | ANAPC13 | chr3:134196547-134204865:- | -0.59 | -8.13 | 1.58E-12 | Height |
| THYM | cis | rs10935120 | 1 | rs11919350 | chr3:134235970 | CEP63 | chr3:134204575-134293852:+ | -0.41 | -5.87 | 6.33E-8 | Height |
| THYM | cis | rs9815354 | 1 | rs11923562 | chr3:41760331 | ULK4 | chr3:41288091-42003660:- | 0.93 | 8.8 | 6.19E-14 | Diastolic blood pressure |
| THYM | cis | rs10935120 | 1 | rs11927068 | chr3:134266321 | ANAPC13 | chr3:134196547-134204865:- | -0.59 | -8.13 | 1.58E-12 | Height |
| THYM | cis | rs10935120 | 1 | rs11927068 | chr3:134266321 | CEP63 | chr3:134204575-134293852:+ | -0.41 | -5.87 | 6.33E-8 | Height |
| THYM | cis | rs10935120 | 1 | rs11928499 | chr3:134232350 | ANAPC13 | chr3:134196547-134204865:- | -0.59 | -8.13 | 1.58E-12 | Height |
| THYM | cis | rs10935120 | 1 | rs11928499 | chr3:134232350 | CEP63 | chr3:134204575-134293852:+ | -0.41 | -5.87 | 6.33E-8 | Height |
| THYM | cis | rs9815354 | 1 | rs11928580 | chr3:41885722 | ULK4 | chr3:41288091-42003660:- | 0.97 | 10.79 | 3.37E-18 | Diastolic blood pressure |
| THYM | cis | rs6911965 | 1 | rs11962469 | chr6:24482421 | ALDH5A1 | chr6:24495197-24537434:+ | 0.33 | 4.17 | 6.75E-5 | Hematological and biochemical traits |
| THYM | cis | rs6911965 | 1 | rs11962469 | chr6:24482421 | GPLD1 | chr6:24428405-24489850:- | 0.57 | 5.56 | 2.44E-7 | Hematological and biochemical traits |
| THYM | cis | rs73726531 | 1 | rs11964408 | chr6:18145907 | NHLRC1 | chr6:18120718-18122851:- | 1.04 | 4.57 | 1.45E-5 | Thiopurine S-methyltransferase activity |
| THYM | cis | rs73726531 | 1 | rs11966998 | chr6:18145733 | NHLRC1 | chr6:18120718-18122851:- | -1.04 | -4.57 | 1.45E-5 | Thiopurine S-methyltransferase activity |
| THYM | cis | rs73726531 | 1 | rs11967496 | chr6:18145750 | NHLRC1 | chr6:18120718-18122851:- | -1.01 | -4.34 | 3.6E-5 | Thiopurine S-methyltransferase activity |
| THYM | cis | rs11971779 | 1 | rs11971779 | chr7:139040258 | C7orf55 | chr7:139025897-139030539:+ | 0.21 | 4.35 | 3.44E-5 | Diisocyanate-induced asthma |
| THYM | cis | rs11976020 | 1 | rs11976020 | chr7:72247800 | TYW1B | chr7:72023729-72298813:- | 1.04 | 12.74 | 2.85E-22 | Educational attainment (years of education) |